BDBM344967 1-[1-(2-fluorophenyl)-1H-::1-[1-(2-fluorophenyl)-1H-indazol-4-yl]-3-{1-[(1-hydroxycyclopropyl)carbon-yl]azetidin-3-yl}imidazolidin-2-one::US9783527, Example 269

SMILES OC1(CC1)C(=O)N1CC(C1)N1CCN(C1=O)c1cccc2n(ncc12)-c1ccccc1F

InChI Key InChIKey=VMIYMEHJZWISFQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 344967   

TargetSodium channel protein type 9 subunit alpha(Human)
Abbvie

US Patent
LigandPNGBDBM344967(1-[1-(2-fluorophenyl)-1H-indazol-4-yl]-3-{1-[(1-hy...)
Affinity DataIC50: 5.79E+3nMAssay Description:Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
US Patent