BDBM345379 (S)-1-ethyl-4-[1-(4-isopropylphenyl)sulfonyl-4-methyl-4,5-dihydroimidazol-2-yl]piperazine::US10202354, Example 44

SMILES CCN1CCN(C2=N[C@@H](C)CN2S(=O)(=O)c2ccc(C(C)C)cc2)CC1

InChI Key InChIKey=IKDOSGHNSMKIPF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 345379   

TargetLysine-specific demethylase 2B(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 345379BDBM345379((S)-1-ethyl-4-[1-(4-isopropylphenyl)sulfonyl-4-met...)
Affinity DataIC50: 0.519nMAssay Description:Full length KDM2B was cloned, expressed, and purified to homogeneity. Compound inhibition of KDM2B demethylase activity was assessed by monitoring th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent