BDBM345444 1-[1-(2,4-difluorophenyl)sulfonyl-4,5-dihydroimidazol-2-yl]-4-ethyl-piperazine::US10202354, Example 109

SMILES CCN1CCN(CC1)C1=NCCN1S(=O)(=O)c1ccc(F)cc1F

InChI Key InChIKey=CPEVXORTDDIANS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 345444   

TargetLysine-specific demethylase 2B(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 345444BDBM345444(US10202354, Example 109 | 1-[1-(2,4-difluorophenyl...)
Affinity DataIC50: 6.33nMAssay Description:Full length KDM2B was cloned, expressed, and purified to homogeneity. Compound inhibition of KDM2B demethylase activity was assessed by monitoring th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent