BDBM345452 1-ethyl-4-[1-(p-tolylsulfonyl)-4,5-dihydroimidazol-2-yl]piperazine::US10202354, Example 117

SMILES CCN1CCN(CC1)C1=NCCN1S(=O)(=O)c1ccc(C)cc1

InChI Key InChIKey=LJBZBZZCXGORJR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 345452   

TargetLysine-specific demethylase 2B(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 345452BDBM345452(US10202354, Example 117 | 1-ethyl-4-[1-(p-tolylsul...)
Affinity DataIC50: 3.76nMAssay Description:Full length KDM2B was cloned, expressed, and purified to homogeneity. Compound inhibition of KDM2B demethylase activity was assessed by monitoring th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent