BDBM345501 Propane-2-sulfonic acid [6-(1-butyl- 5-methyl-6-oxo-1,6-dihydro- pyridin-3-yl)-2-(2,4-difluoro- phenoxy)-pyrimidin-4-yl]-amide::US10202360, Example 46

SMILES CCCCn1cc(cc(C)c1=O)-c1cc(NS(=O)(=O)C(C)C)nc(Oc2ccc(F)cc2F)n1

InChI Key InChIKey=UVHIZXPCFLOAOC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 345501   

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 345501BDBM345501(US10202360, Example 46 | Propane-2-sulfonic acid [...)
Affinity DataIC50: 5.00E+3nMAssay Description:Determination of the IC50 for the CREBBP inhibitors disclosed herein was performed as follows: CREBBP was cloned and expressed in E. Coli as His-tag ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent