BDBM345523 N-(2-(3-chloro-4-methoxyphenoxy)- 6-(1,5-dimethyl-6-oxo-1,6- dihydropyridin-3-yl)pyrimidin-4- yl)propane-2-sulfonamide::US10202360, Example 68

SMILES COc1ccc(Oc2nc(NS(=O)(=O)C(C)C)cc(n2)-c2cc(C)c(=O)n(C)c2)cc1Cl

InChI Key InChIKey=FGVSPTIEOXPGCO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 345523   

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 345523BDBM345523(US10202360, Example 68 | N-(2-(3-chloro-4-methoxyp...)
Affinity DataIC50: 500nMAssay Description:Determination of the IC50 for the CREBBP inhibitors disclosed herein was performed as follows: CREBBP was cloned and expressed in E. Coli as His-tag ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent