BDBM345544 N-(6-(1,4-dimethyl-6-oxo-1,6- dihydropyridin-3-yl)-2-(2,6- dimethylphenoxy)pyrimidin-4- yl)butane-1-sulfonamide::US10202360, Example 89

SMILES CCCCS(=O)(=O)Nc1cc(nc(Oc2c(C)cccc2C)n1)-c1cn(C)c(=O)cc1C

InChI Key InChIKey=MNRFEJDQRBMUPN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 345544   

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 345544BDBM345544(US10202360, Example 89 | N-(6-(1,4-dimethyl-6-oxo-...)
Affinity DataIC50: 500nMAssay Description:Determination of the IC50 for the CREBBP inhibitors disclosed herein was performed as follows: CREBBP was cloned and expressed in E. Coli as His-tag ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent