BDBM345545 N-(6-(2,4-difluorophenoxy)-1',5'- dimethyl-6'-oxo-1',6'-dihydro-[2,3'- bipyridin]-4-yl)propane-2- sulfonamide::US10202360, Example 90

SMILES CC(C)S(=O)(=O)Nc1cc(Oc2ccc(F)cc2F)nc(c1)-c1cc(C)c(=O)n(C)c1

InChI Key InChIKey=YDBVAUQSUDVRPX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 345545   

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 345545BDBM345545(US10202360, Example 90 | N-(6-(2,4-difluorophenoxy...)
Affinity DataIC50: 500nMAssay Description:Determination of the IC50 for the CREBBP inhibitors disclosed herein was performed as follows: CREBBP was cloned and expressed in E. Coli as His-tag ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent