BDBM345560 N-(2-(2,6-dimethylphenoxy)-6-(5- methoxy-1-methyl-6-oxo-1,6- dihydropyridin-3-yl)pyrimidin-4- yl)propane-2-sulfonamide::US10202360, Example 105

SMILES COc1cc(cn(C)c1=O)-c1cc(NS(=O)(=O)C(C)C)nc(Oc2c(C)cccc2C)n1

InChI Key InChIKey=VXNKMLMVNMEAAE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 345560   

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 345560BDBM345560(US10202360, Example 105 | N-(2-(2,6-dimethylphenox...)
Affinity DataIC50: 500nMAssay Description:Determination of the IC50 for the CREBBP inhibitors disclosed herein was performed as follows: CREBBP was cloned and expressed in E. Coli as His-tag ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent