BDBM345683 (2S)-Pentane-2-sulfonic acid [2-(2- chloro-6-fluoro-3-methyl-phenoxy)- 6-(1-methyl-6-oxo-1,6-dihydro- pyridin-3-yl)-pyrimidin-4-yl]-amide::US10202360, Example 228

SMILES CCC[C@H](C)S(=O)(=O)Nc1cc(nc(Oc2c(F)ccc(C)c2Cl)n1)-c1ccc(=O)n(C)c1

InChI Key InChIKey=NNPRCAFQIINDGA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 345683   

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 345683BDBM345683(US10202360, Example 228 | (2S)-Pentane-2-sulfonic ...)
Affinity DataIC50: 500nMAssay Description:Determination of the IC50 for the CREBBP inhibitors disclosed herein was performed as follows: CREBBP was cloned and expressed in E. Coli as His-tag ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent