BDBM345687 4,4,4-Trifluoro-butane-1-sulfonic acid [2-(2-chloro-6-fluoro- phenoxy)-6-(1-methyl-6-oxo-1,6- dihydro-pyridin-3-yl)-pyrimidin-4- yl]-amide::US10202360, Example 232

SMILES Cn1cc(ccc1=O)-c1cc(NS(=O)(=O)CCCC(F)(F)F)nc(Oc2c(F)cccc2Cl)n1

InChI Key InChIKey=NMBCEAJMZKEGMW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 345687   

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 345687BDBM345687(US10202360, Example 232 | 4,4,4-Trifluoro-butane-1...)
Affinity DataIC50: 500nMAssay Description:Determination of the IC50 for the CREBBP inhibitors disclosed herein was performed as follows: CREBBP was cloned and expressed in E. Coli as His-tag ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent