BDBM345719 N-[2-(2-Chloro-6-methyl-phenoxy)- 6-(1-methyl-6-oxo-1,6-dihydro- pyridin-3-yl)-pyrimidin-4-yl]-C- cyclopropyl-methanesulfonamide::US10202360, Example 264

SMILES Cc1cccc(Cl)c1Oc1nc(NS(=O)(=O)CC2CC2)cc(n1)-c1ccc(=O)n(C)c1

InChI Key InChIKey=YKAUKZHQPKCNPT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 345719   

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 345719BDBM345719(US10202360, Example 264 | N-[2-(2-Chloro-6-methyl-...)
Affinity DataIC50: 500nMAssay Description:Determination of the IC50 for the CREBBP inhibitors disclosed herein was performed as follows: CREBBP was cloned and expressed in E. Coli as His-tag ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent