BDBM345723 2-Cyclopropyl-ethanesulfonic acid [2-(2-chloro-6-fluoro-phenoxy)-6- (1-methyl-6-oxo-1,6-dihydro- pyridin-3-yl)-pyrimidin-4-yl]-amide::US10202360, Example 268

SMILES Cn1cc(ccc1=O)-c1cc(NS(=O)(=O)CCC2CC2)nc(Oc2c(F)cccc2Cl)n1

InChI Key InChIKey=JKENHQKTIWJZKE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 345723   

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 345723BDBM345723(US10202360, Example 268 | 2-Cyclopropyl-ethanesulf...)
Affinity DataIC50: 500nMAssay Description:Determination of the IC50 for the CREBBP inhibitors disclosed herein was performed as follows: CREBBP was cloned and expressed in E. Coli as His-tag ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent