BDBM345725 5-(6-amino-2-(2,4- difluorophenoxy)pyrimidin-4-yl)- 1,3-dimethylpyridin-2(1H)-one::US10202360, Example 270

SMILES Cc1cc(cn(C)c1=O)-c1cc(N)nc(Oc2ccc(F)cc2F)n1

InChI Key InChIKey=YLHDBADSSKBQJZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 345725   

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 345725BDBM345725(US10202360, Example 270 | 5-(6-amino-2-(2,4- diflu...)
Affinity DataIC50: 500nMAssay Description:Determination of the IC50 for the CREBBP inhibitors disclosed herein was performed as follows: CREBBP was cloned and expressed in E. Coli as His-tag ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent