BDBM345756 5-[6-(2,5-Dimethyl-benzylamino)-2- (2-fluoro-6-methyl-phenoxy)- pyrimidin-4-yl]-1-methyl-1H- pyridin-2-one::US10202360, Example 301

SMILES Cc1ccc(C)c(CNc2cc(nc(Oc3c(C)cccc3F)n2)-c2ccc(=O)n(C)c2)c1

InChI Key InChIKey=VONCJQWAGHTVHO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 345756   

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 345756BDBM345756(US10202360, Example 301 | 5-[6-(2,5-Dimethyl-benzy...)
Affinity DataIC50: 500nMAssay Description:Determination of the IC50 for the CREBBP inhibitors disclosed herein was performed as follows: CREBBP was cloned and expressed in E. Coli as His-tag ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent