BDBM345760 (R)-5-[2-(2-Fluoro-6-methyl- phenoxy)-6-(1-methyl-butylamino)- pyrimidin-4-yl]-1-methyl-1H- pyridin-2-one::US10202360, Example 305

SMILES CCC[C@@H](C)Nc1cc(nc(Oc2c(C)cccc2F)n1)-c1ccc(=O)n(C)c1

InChI Key InChIKey=WPYWQFKDUPCJOJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 345760   

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 345760BDBM345760(US10202360, Example 305 | (R)-5-[2-(2-Fluoro-6-met...)
Affinity DataIC50: 500nMAssay Description:Determination of the IC50 for the CREBBP inhibitors disclosed herein was performed as follows: CREBBP was cloned and expressed in E. Coli as His-tag ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent