BDBM345764 5-[2-(2-Fluoro-6-methyl-phenoxy)- 6-(3-methyl-butylamino)-pyrimidin- 4-yl]-1-methyl-1H-pyridin-2-one::US10202360, Example 309

SMILES CC(C)CCNc1cc(nc(Oc2c(C)cccc2F)n1)-c1ccc(=O)n(C)c1

InChI Key InChIKey=DBIMXLGUZJREQT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 345764   

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 345764BDBM345764(US10202360, Example 309 | 5-[2-(2-Fluoro-6-methyl-...)
Affinity DataIC50: 500nMAssay Description:Determination of the IC50 for the CREBBP inhibitors disclosed herein was performed as follows: CREBBP was cloned and expressed in E. Coli as His-tag ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent