BDBM345771 2-[4-Butylamino-6-(1-methyl-6-oxo- 1,6-dihydro-pyridin-3-yl)-pyrimidin- 2-yloxy]-3-methyl-benzonitrile::US10202360, Example 316

SMILES CCCCNc1cc(nc(Oc2c(C)cccc2C#N)n1)-c1ccc(=O)n(C)c1

InChI Key InChIKey=DHTCHNCNSOQKKK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 345771   

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 345771BDBM345771(US10202360, Example 316 | 2-[4-Butylamino-6-(1-met...)
Affinity DataIC50: 500nMAssay Description:Determination of the IC50 for the CREBBP inhibitors disclosed herein was performed as follows: CREBBP was cloned and expressed in E. Coli as His-tag ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent