BDBM345822 US10202367, Compound 21::US10202367, Compound 25::US10202367, Compound 26::US10202367, Compound 29::US10202367, Compound 3::US10202367, Compound 63::US10202367, Compound 64

SMILES CC1OC(=NC1CN1CCC(CC1)C(=O)NCCCN1C[C@@H](C)C[C@@H](C)C1)c1ccccc1C

InChI Key InChIKey=APCHXYBRWKAOLC-UHFFFAOYSA-N

Data  7 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 345822   

TargetGenome polyprotein(HCV)
The United States of America, As Represented By The Secretary, Department of Health and Human Services

US Patent
LigandPNGBDBM345822(US10202367, Compound 3 | US10202367, Compound 26 |...)
Affinity DataEC50:  34nMAssay Description:This example demonstrates the EC50 and CC50 values against HCV according to the HCVcc-RLuc reporter assay described in Example 5 and the cytotoxicity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
Go to US Patent

TargetGenome polyprotein(HCV)
The United States of America, As Represented By The Secretary, Department of Health and Human Services

US Patent
LigandPNGBDBM345822(US10202367, Compound 3 | US10202367, Compound 26 |...)
Affinity DataEC50:  59nMAssay Description:This example demonstrates the EC50 and CC50 values against HCV according to the HCVcc-RLuc reporter assay described in Example 5 and the cytotoxicity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
Go to US Patent

TargetGenome polyprotein(HCV)
The United States of America, As Represented By The Secretary, Department of Health and Human Services

US Patent
LigandPNGBDBM345822(US10202367, Compound 3 | US10202367, Compound 26 |...)
Affinity DataEC50:  84nMAssay Description:This example demonstrates the EC50 and CC50 values against HCV according to the HCVcc-RLuc reporter assay described in Example 5 and the cytotoxicity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
Go to US Patent

TargetGenome polyprotein(HCV)
The United States of America, As Represented By The Secretary, Department of Health and Human Services

US Patent
LigandPNGBDBM345822(US10202367, Compound 3 | US10202367, Compound 26 |...)
Affinity DataEC50:  94nMAssay Description:This example demonstrates the EC50 and CC50 values against HCV according to the HCVcc-RLuc reporter assay described in Example 5 and the cytotoxicity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
Go to US Patent

TargetGenome polyprotein(HCV)
The United States of America, As Represented By The Secretary, Department of Health and Human Services

US Patent
LigandPNGBDBM345822(US10202367, Compound 3 | US10202367, Compound 26 |...)
Affinity DataEC50:  125nMAssay Description:This example demonstrates the EC50 and CC50 values against HCV according to the HCVcc-RLuc reporter assay described in Example 5 and the cytotoxicity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
Go to US Patent

TargetGenome polyprotein(HCV)
The United States of America, As Represented By The Secretary, Department of Health and Human Services

US Patent
LigandPNGBDBM345822(US10202367, Compound 3 | US10202367, Compound 26 |...)
Affinity DataEC50:  126nMAssay Description:This example demonstrates the EC50 and CC50 values against HCV according to the HCVcc-RLuc reporter assay described in Example 5 and the cytotoxicity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
Go to US Patent

TargetGenome polyprotein(HCV)
The United States of America, As Represented By The Secretary, Department of Health and Human Services

US Patent
LigandPNGBDBM345822(US10202367, Compound 3 | US10202367, Compound 26 |...)
Affinity DataEC50:  170nMAssay Description:This example demonstrates the EC50 and CC50 values against HCV according to the HCVcc-RLuc reporter assay described in Example 5 and the cytotoxicity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
Go to US Patent