BDBM347710 Methyl 3-[(E)-2-(4-cyanophenoxy)- 3-(dimethylamino)prop-2-enoyl]benzoate::US9790217, 33

SMILES COC(=O)c1cccc(c1)C(=O)C(\Oc1ccc(cc1)C#N)=C/N(C)C

InChI Key InChIKey=XSTZETQRAREPAA-QGOAFFKASA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 347710   

TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM347710(Methyl 3-[(E)-2-(4-cyanophenoxy)- 3-(dimethylamino...)
Affinity DataEC50:  0.0310nMAssay Description:G-402 cells can be obtained from ATCC (CRL-1440) and were originally derived from a renal leiomyoblastoma.The expression plasmids contains the ORF fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM347710(Methyl 3-[(E)-2-(4-cyanophenoxy)- 3-(dimethylamino...)
Affinity DataEC50:  0.0180nMAssay Description:G-402 cells can be obtained from ATCC (CRL-1440) and were originally derived from a renal leiomyoblastoma.The expression plasmids contains the ORF fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent