BDBM347721 4-[[3-[3-(4-Acetylpiperazine-1-carbonyl)phenyl]-1H-pyrazol-4-yl]oxy]benzonitrile::US9790217, 44

SMILES CC(=O)N1CCN(CC1)C(=O)c1cccc(c1)-c1[nH]ncc1Oc1ccc(cc1)C#N

InChI Key InChIKey=ZWQHNTPOKBKIIO-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 347721   

TargetCytochrome P450 11B2, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 347721BDBM347721(4-[[3-[3-(4-Acetylpiperazine-1-carbonyl)phenyl]-1H...)
Affinity DataEC50:  0.313nMAssay Description:G-402 cells can be obtained from ATCC (CRL-1440) and were originally derived from a renal leiomyoblastoma.The expression plasmids contains the ORF fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetCytochrome P450 11B1, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 347721BDBM347721(4-[[3-[3-(4-Acetylpiperazine-1-carbonyl)phenyl]-1H...)
Affinity DataEC50: >30nMAssay Description:G-402 cells can be obtained from ATCC (CRL-1440) and were originally derived from a renal leiomyoblastoma.The expression plasmids contains the ORF fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent