BDBM347880 US9790221, Compound 86

SMILES Cn1cc(-c2cccc(-c3ncc(-c4cnn([C@H]5CC[C@]6(CCC(=O)N6C)CC5)c4)c(NCC4CCNCC4)n3)c2)cn1

InChI Key InChIKey=GZFJWPAKTFWNOW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 347880   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 347880BDBM347880(US9790221, Compound 86)
Affinity DataIC50: 100nMAssay Description:IRAK4 is a human purified recombinant enzyme (His-TEV-IRAK1 (194-712). IRAK4 hydrolyses ATP, autophosphorylates and phosphorylates a Serine/Threonine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 1 [194-712](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 347880BDBM347880(US9790221, Compound 86)
Affinity DataIC50: 3.00E+3nMAssay Description:IRAK1 is a human purified recombinant enzyme (His-TEV-IRAK1 (194-712)). In this assay, IRAK-1 hydrolyses ATP and autophosphorylates. Measurement of I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent