BDBM347881 US9790221, Compound 87

SMILES CN1CCC(CNc2nc(-c3cccc(-c4cnn(C)c4)c3)ncc2-c2cnn([C@H]3CC[C@]4(CCC(=O)N4C)CC3)c2)CC1

InChI Key InChIKey=FOTBDVFUZHABEA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 347881   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 347881BDBM347881(US9790221, Compound 87)
Affinity DataIC50: 100nMAssay Description:IRAK4 is a human purified recombinant enzyme (His-TEV-IRAK1 (194-712). IRAK4 hydrolyses ATP, autophosphorylates and phosphorylates a Serine/Threonine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 1 [194-712](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 347881BDBM347881(US9790221, Compound 87)
Affinity DataIC50: 3.00E+3nMAssay Description:IRAK1 is a human purified recombinant enzyme (His-TEV-IRAK1 (194-712)). In this assay, IRAK-1 hydrolyses ATP and autophosphorylates. Measurement of I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent