BDBM348286 US10577374, Compound 9::US9790229, Compound 9

SMILES O=C(Cc1ccccc1)Nc1cccc(c1)C1CCCN(C1)c1ncnc2[nH]ccc12

InChI Key

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 348286   

TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Sunesis Pharmaceuticals

US Patent
LigandPNGBDBM348286(US10577374, Compound 9 | US9790229, Compound 9)
Affinity DataIC50: >1.00E+4nMAssay Description:The purpose of the BTK in vitro assay is to determine compound potency against BTK through the measurement of IC50. Compound inhibition is measured a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Sunesis Pharmaceuticals

US Patent
LigandPNGBDBM348286(US10577374, Compound 9 | US9790229, Compound 9)
Affinity DataIC50:  4.50E+4nMAssay Description:Reversible inhibition of recombinant full-length N-terminal 6-His-tagged human BTK expressed in baculovirus infected Sf21 insect cells using fluoresc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Sunesis Pharmaceuticals

US Patent
LigandPNGBDBM348286(US10577374, Compound 9 | US9790229, Compound 9)
Affinity DataIC50: >1.00E+4nMAssay Description:BTK-POLYGAT-LS ASSAY. The purpose of the BTK in vitro assay is to determine compound potency against BTK through the measurement of IC50. Compound in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent