BDBM348377 US10577374, Compound 100::US9790229, Compound 100

SMILES Brc1n[nH]c2ncnc(N3CCCC(C3)c3cccc(NC(=O)Nc4ccccc4)c3)c12

InChI Key InChIKey=ZQRXCLHRONADKH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 348377   

TargetTyrosine-protein kinase BTK(Human)
Sunesis Pharmaceuticals

US Patent
LigandPNGBDBM348377(US9790229, Compound 100 | US10577374, Compound 100)
Affinity DataIC50: 5.50E+3nMAssay Description:The purpose of the BTK in vitro assay is to determine compound potency against BTK through the measurement of IC50. Compound inhibition is measured a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Sunesis Pharmaceuticals

US Patent
LigandPNGBDBM348377(US9790229, Compound 100 | US10577374, Compound 100)
Affinity DataIC50: 5.50E+3nMAssay Description:BTK-POLYGAT-LS ASSAY. The purpose of the BTK in vitro assay is to determine compound potency against BTK through the measurement of IC50. Compound in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2020
Entry Details
US Patent