BDBM348419 US10577374, Compound 142::US9790229, Compound 142

SMILES FC(F)(F)c1ccc(Nc2cccc(c2)C2CCCN(C2)c2ncnc3[nH]ccc23)nc1

InChI Key InChIKey=RNLFFQABCOUSHM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 348419   

TargetTyrosine-protein kinase BTK(Human)
Sunesis Pharmaceuticals

US Patent
LigandPNGBDBM348419(US9790229, Compound 142 | US10577374, Compound 142)
Affinity DataIC50: 1.00E+4nMAssay Description:BTK-POLYGAT-LS ASSAY. The purpose of the BTK in vitro assay is to determine compound potency against BTK through the measurement of IC50. Compound in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Sunesis Pharmaceuticals

US Patent
LigandPNGBDBM348419(US9790229, Compound 142 | US10577374, Compound 142)
Affinity DataIC50: 1.00E+4nMAssay Description:The purpose of the BTK in vitro assay is to determine compound potency against BTK through the measurement of IC50. Compound inhibition is measured a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent