BDBM348497 US10577374, Compound 220::US9790229, Compound 220

SMILES O=C(N[C@@H]1CCN(C1)C1CCCN(C1)c1ncnc2[nH]ccc12)Nc1ccccc1

InChI Key InChIKey=WGRJFJBGGCIWTN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 348497   

TargetTyrosine-protein kinase BTK(Human)
Sunesis Pharmaceuticals

US Patent
LigandPNGBDBM348497(US9790229, Compound 220 | US10577374, Compound 220)
Affinity DataIC50: 5.50E+3nMAssay Description:The purpose of the BTK in vitro assay is to determine compound potency against BTK through the measurement of IC50. Compound inhibition is measured a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Sunesis Pharmaceuticals

US Patent
LigandPNGBDBM348497(US9790229, Compound 220 | US10577374, Compound 220)
Affinity DataIC50: 5.50E+3nMAssay Description:BTK-POLYGAT-LS ASSAY. The purpose of the BTK in vitro assay is to determine compound potency against BTK through the measurement of IC50. Compound in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2020
Entry Details
US Patent