BDBM349345 (2R)-2-methyl-9-(5-methyl-1-::US10206931, Example 153

SMILES C[C@@H]1CC(=O)Nc2cccc(-c3cnn(c3C)-c3ccccc3)c2O1

InChI Key InChIKey=MGZAQIJJDQPONH-CYBMUJFWSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 349345   

TargetBromodomain-containing protein 4 [42-168](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM349345((2R)-2-methyl-9-(5-methyl-1- | US10206931, Example...)
Affinity DataIC50:  1.03E+4nMAssay Description:His/Flag epitope tagged BRD4 BD142-168 was cloned, expressed, and purified to. BRD4 binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCREB-binding protein(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM349345((2R)-2-methyl-9-(5-methyl-1- | US10206931, Example...)
Affinity DataIC50:  381nMAssay Description:His/Flag epitope tagged CBP was cloned, expressed, and purified to homogeneity. CBP binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent