BDBM349353 (2R)-9-(5-methoxy-1-methyl-::US10206931, Example 161

SMILES COc1ccc2n(C)c(cc2c1)-c1cccc2NC(=O)C[C@@H](C)Oc12

InChI Key InChIKey=SKSOUXHUSZWKER-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 349353   

TargetCREB-binding protein(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 349353BDBM349353((2R)-9-(5-methoxy-1-methyl- | US10206931, Example ...)
Affinity DataIC50: 161nMAssay Description:His/Flag epitope tagged CBP was cloned, expressed, and purified to homogeneity. CBP binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetBromodomain-containing protein 4 [42-168](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 349353BDBM349353((2R)-9-(5-methoxy-1-methyl- | US10206931, Example ...)
Affinity DataIC50: 6.08E+3nMAssay Description:His/Flag epitope tagged BRD4 BD142-168 was cloned, expressed, and purified to. BRD4 binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent