BDBM351345 1,4:3,6-dianhydro-5-({[4-[(3-chloro-2,4- difluorophenyl)amino]-6- (methyloxy)quinazolin-7-yl]oxy}methyl)-5- deoxy-2-O-methyl-D-xylo-hexitol::US9796704, Entry 45

SMILES CO[C@H]1CO[C@@H]2C(COc3cc4ncnc(Nc5ccc(F)c(Cl)c5F)c4cc3OC)CO[C@H]12

InChI Key InChIKey=JRFNNCFUXZAXOL-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 351345   

TargetEpidermal growth factor receptor(Human)
Symphony Evolution

US Patent
LigandPNGBDBM351345(US9796704, Entry 45 | 1,4:3,6-dianhydro-5-({[4-[(3...)
Affinity DataIC50: 525nMAssay Description:In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent

TargetEphrin type-B receptor 4(Human)
Symphony Evolution

US Patent
LigandPNGBDBM351345(US9796704, Entry 45 | 1,4:3,6-dianhydro-5-({[4-[(3...)
Affinity DataIC50: 1.05E+4nMAssay Description:In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent

TargetEphrin type-A receptor 2(Human)
Symphony Evolution

US Patent
LigandPNGBDBM351345(US9796704, Entry 45 | 1,4:3,6-dianhydro-5-({[4-[(3...)
Affinity DataIC50: 1.05E+4nMAssay Description:In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Symphony Evolution

US Patent
LigandPNGBDBM351345(US9796704, Entry 45 | 1,4:3,6-dianhydro-5-({[4-[(3...)
Affinity DataIC50: 1.05E+4nMAssay Description:In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent