BDBM351379 1,4:3,6-dianhydro-2-deoxy-2-fluoro-5-O-{6- (methyloxy)-4-[(2,4,5- trifluorophenyl)amino]quinazolin-7-yl}-D-iditol::US9796704, Entry 99

SMILES COc1cc2c(Nc3cc(F)c(F)cc3F)ncnc2cc1O[C@@H]1CO[C@H]2[C@H](F)CO[C@@H]12

InChI Key InChIKey=GESHUZBGGLGNGZ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 351379   

TargetEphrin type-B receptor 4(Human)
Symphony Evolution

US Patent
LigandPNGBDBM351379(US9796704, Entry 99 | 1,4:3,6-dianhydro-2-deoxy-2-...)
Affinity DataIC50: 50nMAssay Description:In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
Go to US Patent

TargetEpidermal growth factor receptor(Human)
Symphony Evolution

US Patent
LigandPNGBDBM351379(US9796704, Entry 99 | 1,4:3,6-dianhydro-2-deoxy-2-...)
Affinity DataIC50: 50nMAssay Description:In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
Go to US Patent

TargetEphrin type-A receptor 2(Human)
Symphony Evolution

US Patent
LigandPNGBDBM351379(US9796704, Entry 99 | 1,4:3,6-dianhydro-2-deoxy-2-...)
Affinity DataIC50: 50nMAssay Description:In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
Go to US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Symphony Evolution

US Patent
LigandPNGBDBM351379(US9796704, Entry 99 | 1,4:3,6-dianhydro-2-deoxy-2-...)
Affinity DataIC50: 50nMAssay Description:In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
Go to US Patent