BDBM351395 1,4:3,6-dianhydro-2-deoxy-2-fluoro-5-O-[4- [(4-fluorophenyl)amino]-6- (methyloxy)quinazolin-7-yl]-D-iditol::US9796704, Entry 115

SMILES COc1cc2c(Nc3ccc(F)cc3)ncnc2cc1O[C@@H]1CO[C@H]2[C@H](F)CO[C@@H]12

InChI Key InChIKey=FSNXDZZUWFZSPA-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 351395   

TargetEpidermal growth factor receptor(Human)
Symphony Evolution

US Patent
LigandPNGBDBM351395(US9796704, Entry 115 | 1,4:3,6-dianhydro-2-deoxy-2...)
Affinity DataIC50: 525nMAssay Description:In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent

TargetEphrin type-B receptor 4(Human)
Symphony Evolution

US Patent
LigandPNGBDBM351395(US9796704, Entry 115 | 1,4:3,6-dianhydro-2-deoxy-2...)
Affinity DataIC50: 525nMAssay Description:In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent

TargetEphrin type-A receptor 2(Human)
Symphony Evolution

US Patent
LigandPNGBDBM351395(US9796704, Entry 115 | 1,4:3,6-dianhydro-2-deoxy-2...)
Affinity DataIC50: 525nMAssay Description:In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Symphony Evolution

US Patent
LigandPNGBDBM351395(US9796704, Entry 115 | 1,4:3,6-dianhydro-2-deoxy-2...)
Affinity DataIC50: 1.05E+4nMAssay Description:In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent