BDBM35181 indazole-benzimidazole, 17

SMILES COc1cc(N)ccc1-c1ccc2c(n[nH]c2c1)-c1nc2c(cccc2[nH]1)N1CCN(C)CC1

InChI Key InChIKey=XONAFDRMWJEXGF-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 35181   

TargetCyclin-A2 [177-432]/Cyclin-dependent kinase 2(Homo sapiens (Human))
Pfizer

LigandPNGBDBM35181(indazole-benzimidazole, 17)
Affinity DataIC50:  1.00E+4nMT: 2°CAssay Description:Active cyclin dependent kinase 2 (CDK2) activity was determined by measuring the phosphorylation of Histone type 3 (Sigma H5505), in the presence of ...More data for this Ligand-Target Pair
TargetProtein kinase C zeta type(Homo sapiens (Human))
Pfizer

LigandPNGBDBM35181(indazole-benzimidazole, 17)
Affinity DataIC50:  23.3nMpH: 7.5 T: 2°CAssay Description:Protein kinase C (PKC), zeta activity was measured by following the phosphorylation of a biotinylated peptide substrate in the presence of ATP using ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed