BDBM353166 4-chloro-5-({4-[4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]piperidin-1-yl}methyl)-1,3-thiazol-2-amine::US9796708, Example 398

SMILES COc1ccc(F)cc1-c1ccnc2[nH]c(cc12)C1CCN(Cc2sc(N)nc2Cl)CC1

InChI Key InChIKey=HBPZIWOSOLEZHO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 353166   

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Abbvie

US Patent
LigandPNGBDBM353166(4-chloro-5-({4-[4-(5-fluoro-2-methoxyphenyl)-1H-py...)
Affinity DataIC50: 100nMAssay Description:CDK9 enzyme activities were measured using LANCE ULight TR-FRET kinase assay reagents (PerkinElmer, Waltham, Mass.). Compounds were directly added in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent