BDBM353258 4-(2,5-dichlorophenyl)-2-[1-(methylsulfonyl)-1,2,3,6-tetrahydropyridin-4-yl]-1H-pyrrolo[2,3-b]pyridine::US9796708, Example 490

SMILES CS(=O)(=O)N1CCC(=CC1)c1cc2c(ccnc2[nH]1)-c1cc(Cl)ccc1Cl

InChI Key InChIKey=RSVMMWJYPYWKNV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 353258   

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Abbvie

US Patent
LigandPNGBDBM353258(4-(2,5-dichlorophenyl)-2-[1-(methylsulfonyl)-1,2,3...)
Affinity DataIC50: 640nMAssay Description:CDK9 enzyme activities were measured using LANCE ULight TR-FRET kinase assay reagents (PerkinElmer, Waltham, Mass.). Compounds were directly added in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent