BDBM353954 4-[3-cyano-5-fluoro-4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]cyclohex-3-ene-1-carboxylic acid::US9796708, Example 1186

SMILES COc1ccc(F)cc1-c1c(F)cnc2[nH]c(c(C#N)c12)C1=CCC(CC1)C(O)=O

InChI Key InChIKey=IEWGXCMASDAFLS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 353954   

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Abbvie

US Patent
LigandPNGBDBM353954(4-[3-cyano-5-fluoro-4-(5-fluoro-2-methoxyphenyl)-1...)
Affinity DataIC50: 5.00E+3nMAssay Description:CDK9 enzyme activities were measured using LANCE ULight TR-FRET kinase assay reagents (PerkinElmer, Waltham, Mass.). Compounds were directly added in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent