BDBM355071 6-oxo-2-phenyl-N-{phenyl[4- (trifluoromethyl)phenyl]methyl}-1,6- dihydropyrimidine-4-carboxamide::US9815796, Example 162

SMILES FC(F)(F)c1ccc(cc1)C(NC(=O)c1cc(=O)[nH]c(n1)-c1ccccc1)c1ccccc1

InChI Key InChIKey=CFTYSJAVYOJDHJ-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 355071   

TargetPhosphodiesterase(Rhesus macaque)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM355071(US9815796, Example 162 | 6-oxo-2-phenyl-N-{phenyl[...)
Affinity DataKi:  522nMAssay Description:In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2019
Entry Details
Go to US Patent

TargetPhosphodiesterase(Rhesus macaque)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM355071(US9815796, Example 162 | 6-oxo-2-phenyl-N-{phenyl[...)
Affinity DataKi:  1.00E+3nMAssay Description:In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2019
Entry Details
Go to US Patent