BDBM355105 2-cyclopropyl-6-oxo-N-{phenyl[4- (trifluoromethyl)phenyl]methyl}-1,6- dihydropyrimidine-4-carboxamide::US9815796, Example 196

SMILES FC(F)(F)c1ccc(cc1)C(NC(=O)c1cc(=O)[nH]c(n1)C1CC1)c1ccccc1

InChI Key InChIKey=UAGXUHMSACDUCW-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 355105   

TargetPhosphodiesterase(Rhesus macaque)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM355105(US9815796, Example 196 | 2-cyclopropyl-6-oxo-N-{ph...)
Affinity DataKi:  915nMAssay Description:In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2019
Entry Details
Go to US Patent