BDBM355821 US9815836, Compound 6

SMILES O=C1NCCCCCn2cc(cn2)-c2cccc(c2)C(=O)Nc2cn(nc12)C1CCOCC1

InChI Key InChIKey=SYFRXWMCBTWRPE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 355821   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 355821BDBM355821(US9815836, Compound 6)
Affinity DataIC50: 5.00E+3nMAssay Description:IRAK4 is a human purified recombinant enzyme (His-TEV-IRAK4 (1-460)).In this assay, IRAK4 hydrolyses ATP, autophosphorylates and phosphorylates a Ser...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2019
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 1 [194-712](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 355821BDBM355821(US9815836, Compound 6)
Affinity DataIC50: 5.00E+3nMAssay Description:IRAK1 is a human purified recombinant enzyme (His-TEV-IRAK1 (194-712))In this assay, IRAK1 hydrolyses ATP and autophosphorylates. Measurement of IRAK...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2019
Entry Details
US Patent