BDBM355977 1-(5-chloro-6-(2H- 1,2,3-triazol-2- yl)pyridin-3-yl)-3-(2- chloro-7-((S)-1-(((S)- tetrahydrofuran-3- yl)oxy)ethyl)pyrazolo [1,5-a]pyrimidin-6- yl)urea::US9815842, Example 101
SMILES C[C@H](OC1CCOC1)c1c(NC(=O)Nc2cnc(c(Cl)c2)-n2nccn2)cnc2cc(Cl)nn12
InChI Key InChIKey=RTCANLSNLOZYHV-AMGKYWFPSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 355977
TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Homo sapiens (Human))
Novartis
US Patent
Novartis
US Patent
Affinity DataIC50: 0.00500nMAssay Description:IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ...More data for this Ligand-Target Pair