BDBM355977 1-(5-chloro-6-(2H- 1,2,3-triazol-2- yl)pyridin-3-yl)-3-(2- chloro-7-((S)-1-(((S)- tetrahydrofuran-3- yl)oxy)ethyl)pyrazolo [1,5-a]pyrimidin-6- yl)urea::US9815842, Example 101

SMILES C[C@H](OC1CCOC1)c1c(NC(=O)Nc2cnc(c(Cl)c2)-n2nccn2)cnc2cc(Cl)nn12

InChI Key InChIKey=RTCANLSNLOZYHV-AMGKYWFPSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 355977   

TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM355977(1-(5-chloro-6-(2H- 1,2,3-triazol-2- yl)pyridin-3-y...)
Affinity DataIC50:  0.00500nMAssay Description:IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent