BDBM356849 US10214492, Example 199::US11292767, Example 199

SMILES CCOc1cccc(c1)-c1cc(COC(C)(C)C(O)=O)nn1Cc1ccccc1OCC

InChI Key InChIKey=ZKRCIDHBYNNZTM-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 356849   

TargetMonocarboxylate transporter 4(Human)
Vettore

US Patent
LigandPNGBDBM356849(US10214492, Example 199 | US11292767, Example 199)
Affinity DataIC50: 9.60nMAssay Description:MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetMonocarboxylate transporter 4(Human)
Vettore

US Patent
LigandPNGBDBM356849(US10214492, Example 199 | US11292767, Example 199)
Affinity DataIC50: 9.60nMAssay Description:MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2022
Entry Details
US Patent

TargetMonocarboxylate transporter 1(Human)
Vettore

US Patent
LigandPNGBDBM356849(US10214492, Example 199 | US11292767, Example 199)
Affinity DataIC50: 3.40E+4nMAssay Description:MCT1 activity may be measured using BT-20 breast cancer cells that express high native levels of MCT1, but do not express MCT4 and are known to those...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2022
Entry Details
US Patent

TargetMonocarboxylate transporter 1(Human)
Vettore

US Patent
LigandPNGBDBM356849(US10214492, Example 199 | US11292767, Example 199)
Affinity DataIC50: 3.40E+4nMAssay Description:MCT1 activity may be measured using BT-20 breast cancer cells that express high native levels of MCT1, but do not express MCT4 and are known to those...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent