BDBM357018 (R) 5-(5-chloro-2-(1H-tetrazol-1-yl)phenyl)-2-(25-fluoro-4-oxo-3-aza-1(1,3),2(1,2)-dibenzenacyclononaphane-9-yl)pyridine 1-oxide::US10214512, Example 2-b

SMILES [O-][n+]1cc(ccc1[C@@H]1CCCCC(=O)Nc2ccc(F)cc2-c2cccc1c2)-c1cc(Cl)ccc1-n1cnnn1

InChI Key InChIKey=WRKWQDBVPUMDIA-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 357018   

TargetCoagulation factor XI(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM357018((R) 5-(5-chloro-2-(1H-tetrazol-1-yl)phenyl)-2-(25-...)
Affinity DataKi:  83.1nMAssay Description:The effectiveness of a compound of the present invention as an inhibitor of Coagulation Factor XIa can be determined using a relevant purified serine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent