BDBM357036 US10214512, Example 16::methyl (9-(5-(5-chloro-2- (trifluoromethyl)phenyl)pyridin- 2-yl)-4-oxo-3-aza-1(1,3),2(1,2)- dibenzenacyclononaphane-24- yl)carbamate

SMILES COC(=O)Nc1ccc-2c(NC(=O)CCCCC(c3cccc-2c3)c2ccc(cn2)-c2cc(Cl)ccc2C(F)(F)F)c1

InChI Key InChIKey=WDYCGZICHGRPJO-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 357036   

TargetCoagulation factor XI(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM357036(methyl (9-(5-(5-chloro-2- (trifluoromethyl)phenyl)...)
Affinity DataKi: >875nMAssay Description:The effectiveness of a compound of the present invention as an inhibitor of Coagulation Factor XIa can be determined using a relevant purified serine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
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