BDBM357788 MW-01-148/(I-302)::US10214530, Example 55

SMILES CCn1c2nc(Nc3nc4ccccc4[nH]3)n(Cc3ccccc3)c2c(=O)[nH]c1=O

InChI Key InChIKey=UQFGQSVYFVNQJB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 357788   

TargetTryptophan 5-hydroxylase 1(Human)
Max-DelbrÜCk-Centrum FÜR Molekulare Medizin

US Patent
LigandPNGBDBM357788(MW-01-148/(I-302) | US10214530, Example 55)
Affinity DataIC50: 2.00E+5nMAssay Description:These compounds according to the afore-mentioned examples were tested for tryptophan hydroxylase (TPH) inhibitory activity in a fluorescence-based in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
Go to US Patent

TargetTryptophan 5-hydroxylase 2(Human)
Max-DelbrÜCk-Centrum FÜR Molekulare Medizin

US Patent
LigandPNGBDBM357788(MW-01-148/(I-302) | US10214530, Example 55)
Affinity DataIC50: 2.93E+4nMAssay Description:These compounds according to the afore-mentioned examples were tested for tryptophan hydroxylase (TPH) inhibitory activity in a fluorescence-based in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
Go to US Patent