BDBM358329 5-(1-(tetrahydro-2H-pyran-4-yl)-1H- pyrazol-5-yl)-7-(3-(1-(((tetrahydro-2H- pyran-4-yl)amino)methyl)cyclopropyl) phenyl)pyrrolo[2,1-f][1,2,4]triazin-4- amine::US10214537, Example 398

SMILES Nc1ncnn2c(cc(-c3ccnn3C3CCOCC3)c12)-c1cccc(c1)C1(CNC2CCOCC2)CC1

InChI Key InChIKey=XRAFTFALFSLILE-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 358329   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Bristol-Myers Squibb

US Patent

LigandBDBM358329(US10214537, Example 398 | 5-(1-(tetrahydro-2H-pyra...)Copy SMILESCopy InChI

Affinity DataIC50: 5nMAssay Description:The ADP-Glo format PI3K assays were performed in Proxiplate 384-well plates (Perkin Elmer #6008280). The final assay volume was 2 μl prepared fr...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
10/20/2019
Entry Details
Copy BDB DOIUS Patent

Copy reaction URL