BDBM358412 4-acetyl-1-{3-[4-amino-5-(3-methyl- 1,2-oxazol-5-yl)pyrrolo[2,1-f][1,2,4] triazin-7-yl]phenyl}-3,3- dimethylpiperazin-2-one::US10214537, Example 482

SMILES CC(=O)N1CCN(C(=O)C1(C)C)c1cccc(c1)-c1cc(-c2cc(C)no2)c2c(N)ncnn12

InChI Key InChIKey=GULMUKCPHBYKQA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 358412   

LigandPNGBDBM358412(US10214537, Example 482 | 4-acetyl-1-{3-[4-amino-5...)
Affinity DataIC50: 3nMAssay Description:The ADP-Glo format PI3K assays were performed in Proxiplate 384-well plates (Perkin Elmer #6008280). The final assay volume was 2 μl prepared fr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent