BDBM359912 (S)-tert-butyl (5-((4-fluorophenyl)sulfonyl)-6-methyl-5,6,7,8-tetrahydro-1,5-naphthyridin-3-yl)carbamate (72)::US10221146, Example 72

SMILES CC1CCc2ncc(NC(=O)OC(C)(C)C)cc2N1S(=O)(=O)c1ccc(F)cc1

InChI Key InChIKey=QBJGIKFOMNFKTK-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 359912   

TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent

LigandBDBM359912((S)-tert-butyl (5-((4-fluorophenyl)sulfonyl)-6-met...)Copy SMILESCopy InChI

Affinity DataIC50: 314nMAssay Description:HIS-tagged RORγ-LBD protein was recombinantly expressed in Escherichia coli. The RORγ-LBD protein was purified by Ni2+-affinity resin. Puri...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
10/20/2019
Entry Details
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