BDBM360337 US9828369, Example 2::methyl 3-(8-((2-(4-(trifluoromethyl) phenyl)acetamido)methyl) isoquinolin-5-yl)benzoate

SMILES COC(=O)c1cccc(c1)-c1ccc(CNC(=O)Cc2ccc(cc2)C(F)(F)F)c2cnccc12

InChI Key InChIKey=XBXHAYOZSBUAQW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 360337   

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharpe & Dohme

US Patent
LigandPNGBDBM360337(methyl 3-(8-((2-(4-(trifluoromethyl) phenyl)acetam...)
Affinity DataIC50: 85.6nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2019
Entry Details
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