BDBM360436 US9828369, Example 9::methyl 3-(8-((1-methyl-3-propyl-1H- pyrazole-5-carboxamido)methyl) isoquinolin-5-yl)benzoate

SMILES CCCc1cc(C(=O)NCc2ccc(-c3cccc(c3)C(=O)OC)c3ccncc23)n(C)n1

InChI Key InChIKey=HEBNYVKKOXDSTE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 360436   

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharpe & Dohme

US Patent
LigandPNGBDBM360436(methyl 3-(8-((1-methyl-3-propyl-1H- pyrazole-5-car...)
Affinity DataIC50: 132nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2019
Entry Details
Go to US Patent