BDBM361550 (S)-3-((1R,3S)- 1-(3-chloro-5- fluoro-2-(2- ((3- fluoropropyl) amino)ethoxy) pyridin-4-yl)-3- (trifluoromethyl)- 1,3,4,9- tetrahydro-2H- pyrido[3,4- b]indol-2-yl)- 2- methylpropanoic acid::US10221173, Example 142::US10590132, Example 142::US11046689, Example 142
SMILES C[C@@H](CN1[C@@H](Cc2c([nH]c3ccccc23)[C@H]1c1c(F)cnc(OCCNCCCF)c1Cl)C(F)(F)F)C(O)=O
InChI Key InChIKey=JRFCIWQGFLHMPP-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 361550
Affinity DataIC50: 0.950nMAssay Description:The ability of compounds to down-regulate Estrogen Receptor (ER) numbers was assessed in a cell based immuno-fluorescence assay using the MCF-7 human...More data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMAssay Description:The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha-LBD (GST)) was assessed in competition assays us...More data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMAssay Description:ERα: The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha-LBD (GST)) was assessed in competition...More data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMAssay Description:The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...More data for this Ligand-Target Pair